The Growing Importance of Materials Characterization in Biocompatibility Testing
نویسنده
چکیده
At the heart of these changes is a strong emphasis on the need for ensuring biocompatibility. This heightened awareness of the safety of medical devices has taken on an international character, in large part because of the convergence of FDA regulations and International Organization for Standardization (ISO) standards.1,2As international requirements for the biological evaluation of materials continue to be developed and issued, the use of the chemical characterization of materials to establish biocompatibility will become essential.
منابع مشابه
Synthesis, characterization and biocompatibility evaluation of hydroxyapatite - gelatin polyLactic acid ternary nanocomposite
Objective(s): The current study reports the production and biocompatibility evaluation of a ternary nanocomposite consisting of HA, PLA, and gelatin for biomedical application.Materials and Methods: Hydroxyapatite nanopowder (HA: Ca10(PO4)6(OH)2) was produced by burning the bovine cortical bone within the temperature range of 350-450 oC followed by heating in an oven at 800. Synthesis of the te...
متن کاملResearch Article: Isolation, characterization and biocompatibility evaluation of collagen from Thunnus tonggol skin
Acid-soluble collagen could be isolated from fish skin using acetic acid. In recent years, much attention has been paid to collagen from marine sources, mainly arising from the fact that there is no risk of contagious diseases. Moreover, by processing the fish, significant amounts of waste materials are produced which can be considered as a substitute for these collagen sources. Thunnus tonggol...
متن کاملBSA nanoparticles loaded with IONPs for biomedical applications: fabrication optimization, physicochemical characterization and biocompatibility evaluation
Objective(s): Cancer diagnosis in its early stages of progress, can enhance the efficiency of treatment utilizing conventional therapy methods. Non-biocompatibility of iron oxide nanoparticles (IONPs) has made a big challenge against their usage as a contrast agent. Efficient coverage by biomolecules such as albumin can be a solution to overcome this problem. Herein, albumin-coated IONPs were p...
متن کاملCollagen-chondroitin sulfate-hydroxyapatite porous composites: preparation, characterization and in vitro biocompatibility testing
The aim of this study was to develop two new variants of porous composites based on collagen-chondroitin sulfate-hydroxyapatite (COL-CS-HA) mixtures. Electron microscopy examination showed that the composites had a microporous structure, with HA deposits nonhomogeneously disposed on COL fibrous bundles. Their porosity was higher than 90 % and the biodegradation in the presence of collagenase wa...
متن کاملCharacterization and Corrosion Behavior of Hydroxyapatite- Coated Titanium Substrates Prepared Through Laser Induced Liquid Deposition Technique
Titanium and titanium alloys are often used in orthopedic surgery and dentistry because of their especial characteristics such as biocompatibility, mechanical properties, and corrosion resistance. However, their bio- inertness is the most serious drawback for biomedical applications. Therefore, a bioactive coating like hydroxyapatite (HA) is coated on their surface. In this regard, in the prese...
متن کامل